Kidney diseases and the immune
Purification and typhoid vaccines in getting a full-paratifoid vaccine after immunization because of the abandonment of medical publications nephropathy does not appear anymore.
The shape of a child with proteinuria no rule should not be immunized, the vaccine-related informations post-renal problems, not the doctors who are concerned may be extremely low tolerance against the vaccine caused.
1. Vaccination of renal complications after
On the responses of the kidney to be vaccinated first, in 1916 by NOBECOURTve PEYRE .10 Since then TAB, DT-TAB, flowers, and diphtheria vaccines established connection we've compiled 171 cases of nephropathy.
These complications as clinical symptoms are usually temporary, intermittent or persistent, sometimes within a few hours following the simple application of proteinuria or hematuria occurring in acute nephritis or nephrotic syndrome, or much more rarely seen as a temporary anuria.
Kidney diseases, immunization be considered a contraindication for the systematic.
TAB vaccine immunization initiatives outside the pre-existing renal disease, there is no evidence that violence leads to win.
Kidney disease vaccination
Immunization proteinuria discovered during a major concern, this creates a lot of time. Nephropathy-prone one has a lot of time feared the reaction of the vaccine, the necessity of reaching a decision immunization leads to a withdrawal.
Analysis of the specific findings in children with kidney disease and the vaccine, yet quite insufficient. For this reason, vaccines, isolated, intermittent or continuous events in patients with proteinuria or chronic nephropathy and reliability need to be studied further.
Isolated proteinuria encountered before, it is pathological (the amount of protein in the urine within 24 hours exceeds 50 milligrams) definitely determined. In addition, isolated proteinuria, persistent or intermittent renal examinations will reveal that is recommended. Intermittent proteinuria. This is more common in older children and adolescence and ortostatizm test positive.
Many researchers Orthostatic proteinuria, renal function should be done after examining the opinion that compulsory vaccination complete. Suspected case of kidney function before and after each injection of vaccine as an additional measure of security precautions apply to people.
The isolated and permanently, without qualification postural proteinuria opinions differ: THEROND15 bağışıklamanm made in the form of various doses; LENGRANIN3 and PRUNIER13 recommends against the no.
Hopital des Enfants in Paris, Pierre Malades'dan MAROTEAUX, permanent, if adhered to the protocol on children with isolated proteinuria, renal function have remained unchanged after immunization has found:
Diphtheria-tetanus combined vaccine two weeks apart as a subcutaneous injection:
1. A half-dose
2. A full dose of
3. A full dose of
4. A full dose of
Following the tenth day of each injection, including 24-hour urine test and measurement of proteinuria should be made in Addis count, urine test should be done again 30 days after the last dose.
Poliomiyelit oral vaccine and BCG, is the application of any special control.
French laws, regardless of the type and severity of chronic nephropathy all kinds of real vaccine is considered contraindicated.
However, knowledge of an existing kidney disease worsened after vaccination, there is no evidence showing the statistical meaning to carry.
HAMBURGER and glomerular nephropathy 1966, has created a contraindication for any kind of vaccine and vaccination, the disease will cause more rapid to watch. However, these researchers contraindication break 10 years after the limit, only the active period to cover cases of lipoid nephrosis.
Influenza vaccine, the incidence of clinical or biological symptoms of chronic kidney disease does not cause exacerbation or relapse.PABICO and colleagues 12 and colleagues 11, of influenza infection in renal patients have pointed out a very heavy watches. Although the influenza vaccine, a group of patients receiving immunosuppressive therapy after serological results obtained in the control group was not so satisfactory, but still adequate protection provided against Influenza.
MAROTEAUX 12, periods of remission in children with chronic kidney disease recommend the implementation of a protocol as follows:
Injections made at intervals of two weeks:
1. Diluted to 10% on one-tenth of the vaccine, intradermal subcutaneous dose of 2 to 10% in a diluted
3. One quarter of the dose of vaccine, subcutaneously
4. All of a normal dose, subcutaneously
5. All of a normal dose, subcutaneously
6. All of a normal dose, subcutaneously
Diphtheria and tetanus immune / separately and before the tetanus, diphtheria vaccine is then applied. Previously immunized against diphtheria for children again, Schick test was performed routinely.
By a control examination 10 days after each injection, a 24-hour urine, the amount of extracted protein was measured, and the Addis count, the amount of protein in urine in children older than 10 years 0:10 grams / liter, children under 10 years 0:05 grams / liter there; per minute and 5000 to increase the flow of red blood cell to achieve, reasons for granting immunization stops.
The normal protocols used in the BCG vaccine and oral poliomiyelit. Poliomiyelit vaccine, 20 days after each application of the 24-hour urine protein content was measured and
Addis count was performed.
According to the results of these studies, patients with proteinuria or chronic kidney disease in remission in some cases avoid unnecessary vaccination. If applied carefully, some vaccines, does not damage the renal system.
Isolated, the BCG vaccine in people with intermittent or persistent proteinuria, tetanus, diphtheria, poliomiyelit, measles, rubella and mumps vaccines, no history of kidney problems as well as can be tolerated. The vaccine is harmful to kidney, and kidney disease among people with only typhoid-paratyphoid vaccine should not be made absolutely.
Moreover, vaccines, according to the information we have a few, well-tolerated in cases of chronic kidney disease in remission. However, in these cases, renal function should be checked before and after any immunization. In addition, a dose before the administration of all doses reduced by applying a person's tolerance to the vaccine should be tested.